Biopolymers and cell. 1985. Volume 1. 3. 131 - 134

 

S. V. Kochetkova, M. K. Kukhanova, A. A. Krayevsky

 

PHOSPHORYLATION OF 3'-DEOXY-3'-AMINOTHYMIDINE IN THE MOUSE MYELOMA p38Ag653 CELL CULTURE AND ITS INCORPORATION INTO DNA

 

Summary

 

    The tritium-labelled 3'-deoxy-3'-aminothymidine, an inhibitor of DNA biosynthesis, was shown to penetrate into the mouse myeloma p38Ag653 cell culture. Later on it is phospho-rylated, triphosphorylated and incorporated into DNA, causing the termination of its elongation.

 

Summary in Russian