Biopolymers and cell. 1986. Volume 2. № 3. 147 - 149
D. B. Dorokhov, S. B. Board, Yu. P. Semenkov
THE THIRD SITE OF THE 70S RIBOSOME FOR AMINOACYL-tRNA ANALOGUE BINDING
Summary
The interaction of the stable aminoacyl-tRNA analogue, tRNAPhe—C—C—A(3'NH)-Phe, with 70S ribosome is studied. It is shown that in the presence of poly(U) a ribosome can bind three molecules of tRNAphe—C—C—A(3'NH)-Phe. The «additional» site for binding aminoacyl-tRNA analogue was shown to be similar to the ribosomal E-site for deacylate tRNA.