Biopolymers and cell. 1986. Volume 2. № 4. 206 - 211
Kh. A. Khakimov, A.-K- E. Ergashev, G. P. Makedonov, A. P. Akifjev
PECULIARITIES OF THE MUTAGENIC EFFECT OF y-RAYS AND N-NITROSOMETHYLUREA IN DIFFERENT PERIODS OF THE DNA SYNTHESIS PHASE
Summary
The sensitiveness of the DNA synthesis phase and its different periods to the mutagenic action of ^-irradiation in combination with 5-bromo-2-deoxyuridine (BUDR) and N-nitro-somethylurea was studied in 5-fluorodesoxyuridine-synchronized cells of winter wheat seedlings. In experiments with irradiation the radiosensitizing effect of BUDR in the early S phase was observed. This effect is not found in the middle and late S phases. Such differences in the sensitiveness of different periods of the S phase to the mutagenic action were absent in the experiment with NMU.