Biopolymers and cell. 1986. Volume 2. 4. 215 - 217

 

A. N. Myasnikov, M. N. Smirnov

 

THE YEAST PURINE BIOSYNTHESIS GENES CONTAIN REGULATORY SIGNALS OF THE GENERAL AMINO ACID CONTROL

 

Summary

 

    The promoters of three genes coding for enzymes of purine biosynthesis pathway — ADE1, ADE2 and ADE4 contain a conservative octanucleotide fragment of sequence TGACTCTT. This fragment includes a perfect copy of a consensus sequence for the regulatory site at which the GCN4 gene product binds to the promoters of genes regulated by the general amino acid control — TGACTC.

 

Summary in Russian