Biopolymers and cell. 1989. Volume 5. № 3. 83 - 88

Yu. K. Sykulev, S. Yu. Tetin, S. P. Atamas, \L. I. Matulskaya\, A. F. Panasyuk, G. V. Troitsky

FIBRONECTIN CONFORMATION WITH DIFFERENT IONIC STRENGTH OF THE SOLUTION AS DETERMINED BY CIRCULAR DICHROISM METHODS AND THERMAL-PERTURBATION DIFFERENTIAL SPECTROSCOPY

Summary

    Conformation of plasma fibronectin was determined by circular dichroism and thermal perturbation differential spectroscopy with different ionic strength of the solution. It was found that conformational transition in fibronectin molecule, induced by an increase of the ionic solution strength was followed by no changes in secondary and tertiary stru¬cture of protein but was a result of changes in relative arrangement and domain-domain interaction in space.