Biopolymers and cell. 1989. Volume 5. 5. 100 - 104

 

A. P. Sidorenko, G. A. Khudoly, N. G. Schuppe

 

THE NUCLEOTIDE SEQUENCES PROBABLY CONNECTED WITH THE INITIATION SITES OF DtNA REPLICATION IN DROSOPHILA MELANOGASTER

 

Summary

 

    The DNA fraction enriched in replication initiation sites was isolated from cultured embryonic cells of Drosophila melanogaster using a method of nascent DNA strands extrusion. Hybridization experiments have shown that at least a part of replication initiation sites are repetitive sequences and are highly conservative in evolution.