Biopolymers and cell. 1990. Volume 6. 3. 15 - 24

 

N. N. Vtyurin

 

THE ROLE OF DENSE LOCAL PACKING OF HYDROPHOBIC GROUPS IN P-STRUCTURAL PROTEINS

 

Summary

 

    The study demonstrates that the tendency of hydrophobic groups to the dense local packing on the surface of (5-structural sheets is probably the main reason for the twist of p-structural sheets. To the author's opinion, this fact makes it possible to interpret in a new fashion the architecture of almost all fi-structure-containing domains. The majority of p-structure-containing domains are shown to fall into several clearly-outlined groups with the architectural properties depending on the number and mutual disposition along the chain of the elements of secondary structure ((5-strands and a-helixes) forming the domain.

 

Summary in Russian