Biopolymers and cell. 1990. Volume 6. 4. 102 - 105

 

I. V. Kroupskaya, E. B. Paton

 

INFLUENCE OF RARE CODONS IN THE 5--TERM1NAL REGIONS ON THE EXPRESSION OF GENES RPLJ'-LACZ AND RPLL'-LACZ

 

Summary

 

    Fusion of 5'-terminal fragments of E. coll rpll and rpIL genes to LacZ, has permitted showing that expression of hybrid rplJ'-lacZ and rplL'-lacZ decreases as a result of ap¬pearance of rare GGG and CCC codons in the vicinity of the initiator AUG codon.