Biopolymers and cell. 1990. Volume 6. № 6. 72 - 79

P. V. Kostetsky, I. V. Artemyev, O. I. Pozhiltsova, V. V. Ulyashin

A SOFTWARE PACKAGE FOR ANALYSING AMINO ACID SEQUENCES BY PERSONAL MICROCOMPUTER «ISKRA-226»

Summary

    Presented software package allows: 1) input and edition of amino acid sequences; 2) lis¬ting of aligned amino acid sequences of homologous protein; 3) pairwise comparison of homologous sequences; 4) calculation of phylogenetic trees of homologous protein se¬quences; 5) identification of variable and constant regions of amino acid sequences; 6) search for similarity between two amino acid sequences and list out comparison dot matrix; 7) prediction of B- and T-cell antigenic determinants; 8) trans forming Protein Identification Resource (PIR) from magnetic tape media to «Iskra-226» floppy disk media and vice versa; 9) identification of structure gene fragments using a set of peptides;. 10) translation of structure genes containing introns. Programs are written in BASIC for a personal computer «Iskra-226» (USSR). To accelerate some operations, computer code commands are used. Software package is rea¬lized in interactive mode and intended for specialists on peptide and protein chemistry.