Biopolymers and cell. 1991. Volume 7. № 1. 94 - 101
TSEGELSKY A. A., MYKITYUK R. G., LUTSIK M. D.
Identification and Functional Characteristic of Snail Lectin Receptors on the Surface of Neuroblastoma C 1300 N 18 Cells
The expression and chemical composition of receptors to garden snail lectin (terminal residues of N-acetyl-galactoscamine) on the surface of neuroblastoma C 1300 N 18 cells have been investigated using cytochemical and electorphoretic technique. Receptors are mainly represented by membrane glycoproteins (m. w. 33, 90 and 150 KDa), containing carbohydrate chains of N-type, and to a lesser extent by glycolipids. Receptors were localized on the cell surface as well as in microvilli. The lectin-receptor complexes were subjected to aggregation and endocytosis during 60 minutes, which resulted in rapid decrease of resetting ability with A group red blood cells.