Biopolymers and cell. 1991. Volume 7. № 3. 45 - 49

KASCHEEVA T. K., KUZNETZOVA T. V, RAMSHA U. K., LEBEDEV V. M., IVASCHENKO T. E., BARANOV V. S.

Polymerase Chain Reaction in Prenatal Sexing of the Fetus and in Genotyping of Individual Cells

Summary

    The results of fetus sexing by polymerase chain reaction (PCR) with different Y chromosome specific oligoprimers in chorionic villi samples, amniocytes, in chromosome preparation slide scratchesas well as in maternal blood samples are summerised. Detection of Y chromosome specific sequences in individual human sperms as well as in persons with phenotypic and genotypic derivations in sex differentiation are carried out. Perspective for noninvasive intrauterine fetus sexing by means of PCR with X and Y chromosome specific oligoprimers are discussed.