Biopolymers and cell. 1992. Volume 8. № 6. 41 - 43

BONDARENKO L. B., HARCHENKO O. V., BUTOVICH I. A.

Vitamin D3 and 1,25-dihydroxyvitamin D3—Inhibitors of 5-Lipoxygenase

Summary

    The influence of vitamin D3 and 1,25-(OH)2D3 on the activity of po¬tato 5-lipoxygienase and soy beans 15-lipoxygenase was examined. The inhibitory effect of these compounds on 5-lipoxygenase was established but not 15-lipoxygenase. 1,25-(OH)2D3 was stronger as an inhibitor then vitamin D3. Inhibitory effect of both com¬pounds depended on dose of substrate (linoleic acid).