Biopolymers and cell. 1993. Volume 9. № 4. 26 - 31

DUBEY I. Ya., LJAPINA T. V., GALKIN A. P., FEDORJAK D. M.

Obtaining of the Highly Efficient Polymer Support for the Synthesis of the DNA Fragments on the Basis on the Microspheric Silica «Silochrom-2»

Summary

    New polymer support for the highly efficient oligonucleotide synthesis is proposed. It is based on the microspheric silica «Silochrom-2» with a simple synthetic spacer group between the nucleoside and polymer. On this support a few dozens of oligodeoxyribonucleotides up to 35 bases in length were synthesized successfully.