Biopolymers and cell. 1993. Volume 9. 6. 21 - 30

 

BONDARENKO L. B.

 

Peculiarity of Biological Effects of Vitamin D3 Main Metabolites

 

Summary

 

    The experimental results on peculiarity of biological effects of 1,25-dihydroxyvitamin D3 and 24,25-dihydroxyvitamin D3 — main metabolites of vitamin D3 are summarized in present review. Problems of anatagonism and synergism of their action in whole organism and in separate target cells are discussed. The data on dependence of biological effects characters of each derivative on their doses and cells' physiological state are analysed.