Biopolymers and cell. 1995; 11 (6): 51 - 56

Mutagenesis induced by polynucleotides

Yu. N. Alexandrov

A review of the modern condition of the problem ofmutagenesis by means of polynucleotides of natural and artifical origin. Peculiarities and regularities of their mutagene activity have been characterized. The received results give new information about the nature unstability of genes and the transpositions regularity. The problem of mutagen activity of polynucleotides is being discussed in the field of the gypothesis of insertion mutagenesis.