Biopolymers and cell. 1996; 12 (3): 7 - 16

Mathematical model of mutagenesis dynamics under the action of adenovirus DNA fragment

LUKASH S. I., LUKASH L. L., ZADOROZNYI V. F.

Dynamics of mutagenesis in Chiniese hamster cells under the action of BAV3 DNA fragment containing transforming region is approximized by mathematical formulas on the basis of a model created by us It is shown that a set of parameters might be a foundation for classification as cell systems as their interactions with a mutagen. Variation of parameters and their optimization help us to identify genetic processes which are taking place in the cell population under the action of mutagenic factor and give a possiblility to prognosticate results of cell system - mutagen interaction.