Biopolymers and cell. 1996; 12 (5): 13 - 17

Topological features of potential energy hypersurface of canonical nucleotide bases

D. M. Hovorun, Ya. R. Mishchuk, I. V. Kondratyuk

Topological features of potential energy hypersurface of canonical nucleotide bases calculated by semiem-pirical quantum-chemical AMI method are analysed. Biophysical consequences of these features — cooperatMty, synergysm and adaptability of molecular recognition elementary acts with the nucleic acids participation — are considered.