Biopolymers and cell. 2000; 16 (6): 455 - 467

Mechanisms of apoptosis regulation and antiapoptotic action of oncogenic viruses

A. A. Phllchenkov, Z. A. Butenko

Molecular mechanisms of the apoptosis induction and inhibition are analyzed. Different anti-apoptotic strategies employed by oncogenic viruses are discussed with the emphasis on their importance for viral oncogenesis. Potential therapeutic utility of antiviral agents in cancer treatment is reviewed.