Biopolymers and cell. 2001; 17 (3): 256 - 258

 

 

Cooperative intramolecular H-bonds in quercetine: MNDO/H quantum chemical investigation

 

A. L. Potyahaylo, L. B. Pylypchuk, D. M. Hovorun

 

Formamide and glycerol are known to increase the sequencing efficiency. We compared the ability of different concentration of these co-solvents to improve the sequencing results of GC-rich template. Herein, we report that addition of 5 % formamide and 7.5—JO % glycerol is the most effective for sequencing GC-rich templates.