Biopolymers and cell. 2001; 17 (4): 302 - 307

 

 

Isolation, expression analysis and chromosomal mapping of a novel human kinase gene MLK4

 

S. M. Kvasha, A. I. Protopopov, E. R. Zabarovsky, A. V. Rynditch, V. I. Kashuba

 

Sequencing of 3—8 exons of bcr/abl hybrid gene detected of 5th exon excision (IOS nucleotide) in patient with acute lymphoblastic leukosis with breakpoint in M-bcr. Possible role of such disturbance in development oh Ph' leukosis is discussed.