Biopolymers and cell. 2002; 18 (6): 518 - 521

Gene Cyp2el expression in mouse liver cells exposed to low-dose radiation

O. V. Maksymchuk, 1. M. Danko, I. V. Rosohac'ka, M. O. Chaschyn

This study presents results on gene Cyp2eJ expression peculiarities in mouse liver cells under continued exposure to low-dose radiation. The gene Cyp2el expression and cytochrome P450 relative content were shown to decrease under this exposure. Furthermore, the gene Cyp2eJ expression level was found to depend on the gender and age of animals. The differential expression levels of hepatic gene Cyp2el in the mature mice, suggest that regulation occurs at a trans-criptional or posttranslational level