Biopolymers and cell. Volume 20. № 4. 416-420.

O. V. Maksymchuk, I. M. Danko, L. G. Glushakova, M. O. Chaschyn

Search for possible changes in murine gene Cyp2e1 structural region under exposure to ionizing radiation

Summary

The structural region of murine Cyp2e1 gene was cloned in Escherichia coli system. We identified a nucleotide sequence of gene exon regions of 1482 base pairs. Substitutions, inserts and deletions in the gene structural region revealed by sequencing appeared to be invalid. Thus, low doses of Chernobyl specter radiation do not cause changes in the nucleotide sequence of structural region of murine cytochrome P450 2E1 gene.