Biopolymers and cell. 2005; 21 (1): 60 - 63

Changes in the glial fibrillary acidic protein concentration in the medial part of vision tuber under the generation of conditioned reaction of active avoidance

O.L. Drozdov, V. I. Chornaya

The changes in concentration of glial fibrillary acidic protein (GFAP), a marker of glial intermediate filaments in astrocytes of medial part of vision tuber, are studied for the rat brain during generation of conditioned reaction of active avoidance. The increase in GFAP level in membrane fractions of medial part of vision tuber has been shown to be statistically significant in 2 hrs and 24 hrs after the start of training. The data obtained suggest the GFAP participation in the processes connected with learning and memorization.

Key words: learning, memory, glial fibrillary acidic protein.