Biopolymers and cell. 2005; 21 (3): 283 - 286

About molecular mechanisms of fiber muscle contraction at transition to new equilibrium state: analysis of experimental data using three-componential electrical stimulating signal

D. N. Nozdrenko, K. I. Bogutska

Molecular mechanisms of muscular fiber contraction from native conditions of rest are found to be more complex in comparison with those from conditions of preliminary pressure. An application of three-component electrical stimulating signal has revealed non-linearity of dynamic processes during an appropriate phase before tetanus contraction. It is possible that the slipping of actin and myosin protofibrils occurs with the formation of strong bounds of myosin heads with actin, which starts at the contraction from the rest state. The revealed non-linear dynamic characteristics of muscle contraction proof the complexities in creation of its adequate microstructural model.

Key words: muscle contraction, muscular fiber, force, length, electrical stimulation, actin, myosin.