Biopolymers and cell. 2007; 23 (3): 188 - 201

 

 

Nature and origin of germline mutations in human tandem repeated loci

 

S. A. Kravchenko, L. A. Livshits

 

The literature and own data on nature and origin of germline mutations in human hypervariable mini- and microsatellite loci have been analyzed. Possible molecular mechanisms involved in the mutation process in genomic loci with different nature are discussed.

 

Keywords: minisatellite and microsatellite loci, germline mutations, mutation rate