Biopolymers and cell. 2010; 26 (4): 265 - 272
Expression and structural-functional alterations of α-1-acid glycoprotein at the pathological state
N. I. Stekleneva, A. I. Shevtsova, O. Z. Brazaluk, A. O. Kulinich
Dnipropetrovsk State Medical Academy 9 Dzerzhinsky Street, Dnipropetrovsk, Ukraine, 49044
The review analyzes up-to-date knowledge on structure and biological functions of α-acid glycoprotein. The special attention is given to alterations of fucosylation, sialylation and branching of orosomucoid at the acute, chronic inflammation and oncotransformations.
Keywords: α-acid glycoprotein, glycosylation, inflammation, oncopathology.