Biopolym. Cell. 1997; 13(2):113-115.
Structure and Function of Biopolymers
Gene expression for two glutathione transferase isoforms in placenta of women from Ukraine regions with various radioactive pollution
1Prima V. I., 1Melnik N. A., 1Martynenko E. I., 1Bartish G. V., 1Tchaikovskaya T. L., 1Obolenskaya M. Yu.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680


The accumulation of mRNA for π and μ isoforms of GT was studied in placenta of women from regions with various degree of radioactive pollution due to Chernobyl disaster. By means of DNA-RNA hybridization it was shown that long living on polluted territory causes the decrease of mRNA content for both GT isoforms but the effect is stronger for GT π representing the main pan of this link of placental cells detoxification system


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