Biopolym. Cell. 1996; 12(5):66-71.
PCR amplification, cloning and sequencing of cDNA fragment encoding a nucleotide binding domain of mammalian tyrosyl-tRNA synthetase
1Levanets O. V., 1Naidenov V. G., 1Woodmaska M. I., 1Odynets K. A., 1Matsuka G. H., 1Kornelyuk A. I.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680


cDNA fragment encoding the N-terminal nucleotide binding domain (Rossmann fold) of mammalian tyrosyl-tRNA synthetase has been PCR-amplified, cloned and sequenced. The unique variant of conservative HIGH-like motif, HVA Y, where glycine residue was substituted by alanine, has been observed for the first time.


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