Biopolym. Cell. 1999; 15(1):63-66.
Viruses and Cell
Induction of the phage resistance in the progeny of an infected bacterial cell
1Pererva T. P.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03680


Using bacteriophages MS2, P17 and λ-vir infecting Escherichia call AB 259 (Hfr 3000), E. coli MIT and E. coli C600 cells appropriately the author demonstrates that both RNA- and DNA-containing piiages induce the development of phase-resistant forms appearing with high frequency in the progeny of infected cells.


[1] Lederberg J, Lederberg EM. Replica plating and indirect selection of bacterial mutants. J Bacteriol. 1952;63(3):399-406.
[2] Pererva TP. Resistance to phage MS2 induced in E. coli by infection with that phage. Tsitol Genet. 1977;11(1):3-9.
[3] Jacob F, Wollman E. Gender and genetics in bacteria. M Izdatel'stvo inostrannoy lit-ry, 1962. 475 p.
[4] Hirota Yu. The effect of acridine dyes on mating type factors in Escherichia coli. Proc Natl Acad Sci USA. 1960;46(1):57-64.
[5] Lederberg J, Cavalli LL, Lederberg EM. Sex compatibility in Escherichia coli. Genetics. 1952;37(6):720-30.
[6] Orosz L. Phage-resistant R-factor with geretic transfer ability. Acta Microbiol. Acad. Sci. Hung. 1972. 22(3):359.
[7] Lawn AM, Meynell GG, Meynell E, Datta N. Sex pili and the classification of sex factors in the enterobacteriaceae. Nature. 1967;216(5113):343-6.
[8] Rappaport I. Some studies of the infectious process with MS2 bacteriophage. Biochim Biophys Acta. 1965;103(3):486-94.
[9] Strauss JH Jr, Sinsheimer RL. Purification and properties of bacteriophage MS2 and of its ribonucleic acid. J Mol Biol. 1963;7:43-54.
[10] Pererva T. P., Miryuta N. Yu., Miryuta A. Yu. MS2 phage lysogeny. Phage-specific RNA synthesis on cell DNA Biopolym. Cell. 1993; 9(1):45-50
[11] Pererva T., Mirjuta N., Mirjuta A., Woodmaska M., Zherebtsova E. Lysogeny by MS2 phage. Analysis of a recombinant plasmid containing MS2 RNA-like sequence. Biopolym. Cell. 1995;11(1):61-65
[12] Gershenzon SM. [The selectivity of the mutagenic action of DNA and other polynucleotides]. Zh Obshch Biol. 1996;57(6):661-83.
[13] Karpova I. S., Pidpala O. V. Genetic instability in Bacillus subtilis, induced by foreign DNA mutagenic action of natural and synthetic nucleotides. Kiev: Naukova Dumka, 1990:48-71.
[14] Karpova IS, Pidpala OV, Shul'zhenko VN, KostetskiД­ IE, Koretskaia NV, Lukash LL. The mutagenic activity of the DNA of recombinant plasmids in a competent Bacillus subtilis culture. Tsitol Genet. 1994;28(1):66-73.
[15] Hall BG. Adaptive evolution that requires multiple spontaneous mutations. I. Mutations involving an insertion sequence. Genetics. 1988;120(4):887-97.