Biopolym. Cell. 1986; 2(4):215-217.
Short Communications
The yeast purine biosynthesis genes contain regulatory signals of the general amino acid control
1Myasnikov A. N., 1Smirnov M. N.
  1. Department of Genetics of the A. A. Zhdanov Leningrad State University
    Leningrad, USSR


The promoters of three genes coding for enzymes of purine biosynthesis pathway – ADE1, ADE2 and ADE4 contain a conservative octanucleotide fragment of sequence TGACTCTT. This fragment includes a perfect copy of a consensus sequence for the regulatory site at which the GCN4 gene product binds to the promoters of genes regulated by the general amino acid control – TGACTC.


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