Biopolym. Cell. 2008; 24(4):286-293.
Structure and Function of Biopolymers
Min-like protein of Drosophila virilis and its mutant forms: primary structure and possible functional role
1Zhuk O. W., 1Kozeretska I. A., 1Sivolob A. V.
  1. Taras Shevchenko National University of Kyiv
    64, Volodymyrska Str., Kyiv, Ukraine, 01601


The primary structure of Min-like protein – product of miniature-like gene of D. virilis – was predicted by genome sequences analysis, further confirmed by the mRNA sequencing. The high conservatism of the protein in some insects was demonstrated. We analyzed the sites necessary for Min-like protein functioning. The investigation of gene expression in mutant ml42 and mlG1 females showed the presence of whole-size transcripts, the determination of their primary structure allowed us to suggest the grounds of mutant phenotype appearance.
Keywords: Drosophila virilis, proteins with ZP domain, functional regions, maternal effect, evolutional conservatism


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