Biopolym. Cell. 2012; 28(5):338-351.
Allelic polymorphism of glucocorticoid receptor NR3C1 (GR): from molecular biology to clinical implications
1Orlovsky M. A.
  1. O. O. Bogomoletz Institute of Physiology, NAS of Ukraine
    Akademika Bogomoltsa Str., 4, Kyiv, Ukraine, 01004


Polymorphism of stress-related genes is a key factor determining difference in the stress reactivity and resistance among humans. Glucocorticoid receptors are important actors of stress responses. This review is focused on the molecular biology and clinical implications of glucocorticoid receptor gene polymorphism.
Keywords: glucocorticoid receptors, allelic polymorphism, SNP, NR3C1, GR, stress-induced pathology


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