Biopolym. Cell. 1987; 3(3):134-136.
Short Communications
Studies in replication of plasmids containing SV40 genome in mammalian cells
1Landau S. M., 1Sasina L. K., 1Chashchin N. A., 1Chashchina L. I.
  1. Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR
    Kiev, USSR


The replication of the bacterial recombinant plasmids containing SV40 genome has been studied in cultures of simian CVI cells. It is shown that replication of recombinant DNAs having "poison sequences" may be induced by introduction of the vacuolating SV40 virus simultaneously with chimeric plasmids containing SV40 genome.


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[3] Lusky M, Botchan M. Inhibition of SV40 replication in simian cells by specific pBR322 DNA sequences. Nature. 1981;293(5827):79-81.
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