Biopolym. Cell. 2022; 38(2):117-142.
About MSC
1Kordium V. A., 1Irodov D. M.
  1. Institute of Molecular Biology and Genetics, NAS of Ukraine
    150, Akademika Zabolotnoho Str., Kyiv, Ukraine, 03143


The interest in MSCs is rapidly growing due to their possible and actual therapeutic properties. In terms of scientific studies and clinical application, primary attention is paid to the issues, related to the use of MSCs as a therapeutic means. Successful advance in this direction requires the understanding of the place of MSCs in the organism and those factors which caused the need for the evolutionary manifestation of the functions performed by special cells – MSCs. Thus, current notions about the mechanisms of the therapeutic effect of MSCs are considered here. These notions are compared to the experimental data about the phenomenology of therapeutic effects, registered after the administration of MSCs into the organism as a therapeutic means. The information on the special role of MSCs in the organism is analyzed, and the idea is formed about the essence of this special role. Based on the conducted analysis, the suggestion is made about directing the studies into enhancing the therapeutic effects of MSCs as a potentially highly efficient medicinal agent.
Keywords: MSC


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