Biopolym. Cell. 1990; 6(1):88-90,106.
Studies in expression of human exogenous insulin gene under control of regulatory region of hsp70 dr. melanogaster gene in human fibroblasts
1Neborachko L. N., 1Lukash L. L., 1Varzanova I. S., 1Kordium V. A.
  1. Institute of Molecular Biology and Genetics, Academy of Sciences of the Ukrainian SSR
    Kiev, USSR


A vehicle has been constructed where the human insulin gene is under control of the regulatory region of hspJO Dr. melanogaster gene. The expression of this gene in human fibroblasts under the effect of heat shock has been studied. It is shown that four-fold increase in the expression of the human insulin gene is observed in response to heat shock.


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