Biopolym. Cell. 1992; 8(6):30-34.
Structure and Function of Biopolymers
Protein biosynthesis in cell-free systems from rabbit liver under experimental myocardial ischemia
1Mashanauskas T. K., 1Ivanov L. L., 1Rodovichius H. A., 1Lukoshevichius L. J., 1Prashkevichius A. K.
  1. Kaunas Medical Academy
    Mizkevicha Str. 9, Kaunas, Lithuania, 44307


The level of protein biosynthesis in cell-free systems from rabbit liver was studied both in norm and 12 h after experimental myocardial ischemia (EMI). The results demonstrate that the rise in the level of [14C]-leucine incorporation into translational product in cell-free system under EMI is related to the increase of aminoacyl-tRNA synthetase activity. Electrophoretical analysis of the translational products with subsequent fluorography has revealed redistribution in the spectrum of the proteins synthesized in cell-free system under EMI.


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