Biopolym. Cell. 1996; 12(6):25-35.
http://dx.doi.org/10.7124/bc.000452
Вплив гетерогенності системи соматичних клітин ссавців на прояв мутагенезу, індукованого трансформуючими генами аденовірусу
1Лукаш С. І., 2Лукаш Л. Л.
  1. Інститут кібернетики імені В. М. Глушкова НАН України
    Проспект Академіка Глушкова, 40, Київ, Україна, 03680
  2. Інститут молекулярної біології і генетики НАН України
    Вул. Академіка Заболотного, 150, Київ, Україна, 03680

Abstract

На підставі аналізу літературних та власних даних запропоновано математичну модель прояву індукованого мутагенезу, яка враховує клітинну гетерогенність по періоду генерації в системі онкогенний аденовірус – соматична клітина ссавців. Досліджено вплив деяких параметрів, використаних для побудови математичної моделі, на динаміку мутагенезу. Результати теоретичних розрахунків порівнюються з експериментальними даними.
Повний текст: (PDF, російською)

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