Biopolym. Cell. 1987; 3(1):3-17.
http://dx.doi.org/10.7124/bc.0001CD
Огляди
Антисенсові РНК: новий механізм регуляції генної експресії
1Швед А. Д., 1Золотухін С. Б., 1Мацука Г. Х.
  1. Інститут молекулярної біології і генетики АН УСРС
    Київ, СРСР

Abstract

Огляд присвячено стану питання про нещодавно відкритий новий механізм регулювання генної експресії, заснований на РНК:РНК-взаємодії. Наведено відомості про виявлені в природі приклади регуляторної функції антисенсових РНК, про загальні принципи конструювання штучних антисенсових регуляторних систем, а також представлено аналіз робіт, присвячених експериментальній перевірці активності різних антнсенсових РНК-транскриптів у репресії окремих генів.
Повний текст: (PDF, російською)

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